RNA is involved in regulation in the cell at many levels. miRNA species control gene regulation in higher organisms, and there are related systems such as CRISPR in bacteria and archae. These systems are exploited as powerful tools in biology, such as RNA interference (siRNA). RNA regulation is also important at the level of control of translation, RNA processing, splicing and alternative splicing, RNA degradation, site-specific RNA modification by snoRNAs and gene regulation by riboswitches and ribozymes (RNA catalysis).
The underlying pathways and mechanisms of these processes are becoming understood at a structural level. In this meeting we plan to discuss these RNA-based control phenomena predominantly from a mechanistic and structural perspective.
The underlying pathways and mechanisms of these processes are becoming understood at a structural level. In this meeting we plan to discuss these RNA-based control phenomena predominantly from a mechanistic and structural perspective.
